SS-31 (Elamipretide)

What is it?

SS-31 is a mitochondrial-targeted peptide designed to improve cellular energy production and reduce oxidative stress. It is commonly used for energy support, recovery, anti-aging, and mitochondrial health.

Key Benefits

• Strong mitochondrial and energy support

• Helps reduce oxidative stress and inflammation

• Supports cognitive function and recovery

• May improve metabolic and cardiovascular health

• Supports healthy aging and cellular repair

Possible Side Effects

Usually mild:

• Injection site irritation

• Headache

• Dizziness

• GI upset or bloating

Rare but serious:

• Allergic reactions

• Rapid heartbeat

• Severe weakness or confusion

• Vision disturbances

Seek medical attention if severe symptoms occur.

Contraindications

Do not use if:

• Pregnant or breastfeeding

• Hypersensitive to mitochondrial-targeted compounds

SS-31 Dosing Protocols

General Guidelines

• Subcutaneous injection

• Best taken fasted

• Morning dosing preferred

• Cycle length: 8 to 12 weeks

• Washout: 4 to 8 weeks

10mg Vial Protocol

Commonly used before MOTS-C cycles

Reconstitution

Mix:

• 10mg vial + 1mL (100 units) BAC water

Dosing

• 10 units daily

• For 10 to 14 days before starting MOTS-C

30mg Vial Protocols

Reconstitution

Mix:

• 30mg vial + 2mL (200 units) BAC water

Low Dose Protocol

Week 1

• 7 units (1mg), daily, 5x weekly

Weeks 2 to 5

• 14 units (2mg), daily, 5x weekly

Weeks 6 to 8

• 21 units (3mg), daily, 3x weekly

Weeks 9 to 12

• 28 units (4mg), daily, 3x weekly

Standard Protocol

• 33 units (5mg)

• 3 to 7 times weekly

• For 8 to 12 weeks

Maximum Protocol

Week 1

• 10 units (1.5mg), daily, 5x weekly

Weeks 2 to 5

• 20 units (3mg), daily, 5x weekly

Weeks 6 to 8

• 30 units (4.5mg), daily, 3x weekly

Weeks 9 to 12

• 40 units (6mg), daily, 3x weekly

50mg Vial Protocols

Reconstitution

Mix:

• 50mg vial + 3mL (300 units) BAC water

Low Dose Protocol

Week 1

• 6 units (1mg), daily, 5x weekly

Weeks 2 to 5

• 12 units (2mg), daily, 5x weekly

Weeks 6 to 8

• 18 units (3mg), daily, 3x weekly

Weeks 9 to 12

• 24 units (4mg), daily, 3x weekly

Standard Protocol

• 30 units (5mg)

• 3 to 7 times weekly

• For 8 to 12 weeks

Maximum Protocol

Week 1

• 9 units (1.5mg), daily, 5x weekly

Weeks 2 to 5

• 18 units (3mg), daily, 5x weekly

Weeks 6 to 8

• 27 units (4.5mg), daily, 3x weekly

Weeks 9 to 12

• 36 units (6mg), daily, 3x weekly

Suggested Stacks

• MOTS-C for mitochondrial and metabolic support

• NAD+ for cellular energy and recovery

• Glutathione for antioxidant support

• CJC-1295 + Ipamorelin for recovery and regeneration

• AOD-9604 for metabolic support

• BPC-157 for systemic recovery