Cagrilintide (Cagri)

What is it?

Cagrilintide is a long-acting amylin receptor agonist used for appetite suppression and weight loss. It works by increasing satiety, slowing gastric emptying, and improving appetite control. It is commonly stacked with GLP-1 agonists for enhanced fat loss results.

Key Benefits

• Strong appetite suppression

• Enhances weight loss and fat reduction

• Helps control cravings and portion sizes

• Slows gastric emptying for longer fullness

• Works synergistically with GLP-1 agonists

Expected Outcomes

• 6 to 10% body weight reduction with Cagri alone

• Greater weight loss when combined with GLP-1s

• Often used as a plateau breaker during GLP-1 therapy

Possible Side Effects

Common:

• Nausea

• Constipation

• Fatigue

• Headache

• Diarrhea

• Injection site irritation

Less common:

• Vomiting

• Heartburn

• Gallstones

Important Notes

• Dose once weekly

• Use on the same day each week

• Stay hydrated during cycle

• Do not exceed 12 consecutive weeks without a break

Cagrilintide Dosing Protocol (10mg)

Reconstitution

Mix:

• 10mg vial + 2mL (200 units) BAC water

Concentration

• 4 units = 200mcg

• 8 units = 400mcg

• 15 units = 750mcg

• 24 units = 1.2mg

• 34 units = 1.7mg

• 44 units = 2.2mg

• 54 units = 2.7mg

Standard Protocol

Week 1

• 4 units (200mcg)

Week 2

• 8 units (400mcg)

Week 3

• 15 units (750mcg)

Week 4

• 24 units (1.2mg)

Week 5

• 34 units (1.7mg)

Week 6

• 44 units (2.2mg)

Weeks 7 to 8

• 54 units (2.7mg)

Cycle Length

• 8 weeks on

• 4 to 8 weeks washout

Suggested Stacks

• Semaglutide

• Tirzepatide

• Retatrutide for advanced fat loss protocols

• Tesofensine for appetite and thermogenesis support

• AOD-9604 for additional fat metabolism support